*This listing is for the printed version of this publication*
 
Medical Cannabis & Epilepsy offers a comprehensive and evidence-based guide for healthcare professionals, patients, regulatory bodies, and anyone seeking to understand the role of cannabis-based medicinal products (CBMPs) in treating epilepsy. 
 
This publication explores the latest research, clinical trials, and real-world evidence on how cannabinoids, particularly CBD, can impact epilepsy treatment, especially in cases of drug-resistant epilepsy. It provides in-depth analysis of the challenges faced in accessing medical cannabis within the highly regulated UK framework. Medical Cannabis & Epilepsy outlines gaps in NHS access, the reliance on private clinics, and the significant financial burden faced by families seeking treatment with cannabis-based medicinal products (CBMPs). It also highlights the critical role of real-world evidence in supporting the broader acceptance and understanding of CBMPs for epilepsy treatment, especially for those patients who do not respond to traditional anti-seizure medications.
 
Medical Cannabis & Epilepsy contains an extensive review of scientific evidence, summarising nearly 100 clinical trials, real-world studies, case reports, observational studies, and randomised controlled trials. With this publication, the authors provide a robust foundation for understanding the efficacy and safety of cannabis in epilepsy treatment.
 
Key Features:
In-Depth Overview of Epilepsy: Covers the classification, causes, and clinical presentation of epilepsy, providing a foundational understanding for healthcare professionals and patients alike
Mechanisms of Action: Explains how cannabinoids like CBD, THC, and terpenes modulate brain pathways, including neurotransmitters like GABA and glutamate, to reduce neuronal excitability and seizure frequency.
Second Generation CBMPs: Explains how cannabinoids like CBD and other terpenes interact with brain receptors to reduce seizures, including an exploration of how cannabinoids can modulate excitatory and inhibitory pathways in the brain.
THC Use in Children with Epilepsy: Addresses concerns around the safety of THC and explores the evidence.
Drug-Drug Interactions: Explores the potential interactions between medical cannabis and conventional anti-seizure medications, helping clinicians make informed decisions when integrating CBMPs into a patient's treatment plan.
Importance of Real-World Evidence: Highlights the value of patient-reported outcomes and real-world data, which offer additional insights that traditional clinical trials may overlook, particularly in understanding long-term efficacy and safety in diverse populations.
Evidence Review & Real-World Studies: Features an extensive review of clinical and real-world evidence, and over 280 references to peer-reviewed literature, ensuring that readers have access to the most up-to-date research.